Crowds out bacterial pathogens
Supports the normal immune function of intestinal cells (1). Maintains healthy gut flora by crowding out bacterial pathogens to allow proliferation of beneficial bacteria (2). Produces quorum-sensing molecules that communicate to intestinal cells to help maintain tight junctions and intestinal barrier function (3). Promotes proper digestion and nutrient absorption by supporting the normal breakdown of complex carbohydrates and fats.
Promotes healthy serum cholesterol levels
Supports maintenance of healthy serum cholesterol levels (4), improves abdominal pain and bloating associated with irritable bowel syndrome patients (5), increases immune response to viral challenges (6). May be effective in treating and preventing C. difficile associated diarrhea (7).
Decreases frequency of vaginal yeast infections
Prevents the overgrowth of pathogenic microorganisms and protects against occasional bouts of diarrhea, gas and bloating (8). Relieves symptoms associated with Irritable Bowel Syndrome (9) Decreases the frequency of vaginal yeast infections and urinary tract infections (10).
Supports healthy immune system function
Enhances natural immune function in healthy individuals (11). Increases the proportion of total helper and activated T cells and other important immune modulating cells (12). Has an immune-modulatory effect in individuals suffering from seasonal allergic rhinitis resulting in diminished allergic symptoms (13).
Decreases stress-induced gastrointestinal discomfort
Supports stress reduction
Supports gut-brain health by reducing stress-induced anxiety and depression-related behavior in animal models (16). Recent studies have shown that at least one strain of L. rhamnosus may contribute to weight loss in women who are dieting (17). Other studies have demonstrated that strains may support skin heath (18) and protect against various infectious diarrhea’s (19).
Promotes good dental health
Supports host immune responses
Establishes a mutualistic relationship with intestinal cells and modulates host immune responses, supporting normal immune function even during stressful challenges such as pathogen invasion (24). Suppresses the expression of inflammatory mediators in intestinal epithelial cells (25).
Promotes healthy digestion of nutrients
One of the first colonizers of the human gastrointestinal tract, B. breve strains are numerically prevalent in healthy breast-fed infants. Assists in the breakdown and fermentation of some plant polysaccharides that cannot be digested by humans. Generates short chain fatty acid metabolites that have anti-inflammatory and anti-tumor properties (26, 27).
Promotes healthy intestinal barrier function
Keeps disease-causing microorganisms from flourishing. Supports healthy intestinal barrier function to prevent harmful bacteria from entering the bloodstream. Maintains intestinal lining and is one of several probiotics that may be useful in treating Irritable Bowel Syndrome (28).